Research headed by Dr. Jeffery Weise at Tulane University
has indicated that Tex-OE, a derivative of the prickly pear
fruit, may help people suffering from alcohol hangovers. Researchers
collected data at “typical-style college barbecue parties” on
the Tulane campus.
The group studied was composed of 55 graduate medical students;
half of the students were given Tex-OE extract and half were
given a placebo. The students consumed five-10 alcoholic beverages
each. The study did not specify the alcohol content of the
beverages used in the study, and it did not specify how long
allowed to drink.
The researchers published a report on their findings which
appeared in the June 2004 issue of the Archives of Internal
a publication of the American Medical Association.
The results of the Tulane study are encouraging, showing that
individuals who took Tex-OE extract before drinking alcohol
were half as likely to experience severe hangovers. Students
Tex-OE experienced fewer headaches and less dry mouth, fatigue,
and nausea than those who received the placebo. What’s
more, the study revealed that Tex-OE also improved cognitive
functioning the day after drinking.
The extract of the cactus fruit contains high levels of heat
shock proteins (HSPs), an element of all living organisms
that protects against the degenerative effects of physical
HSPs are normally produced by the body to counteract stress
and to heal body damage caused by physical stress.
Perfect Equation, Inc., which holds exclusive rights to Tex-OE,
has used it to create a product called the Hangover Prevention
Formula (HPF). The formula utilizes the HSPs found in the
cactus fruit to reduce hangover effects.
Recommended dosage is one capsule per 130 pounds of bodyweight
two hours before drinking in order to prevent the damage
that is usually caused by alcohol (and the subsequent hangover).
One may purchase two capsules for $5.95 or 10 capsules
Each dose lasts three days.
The Perfect Equation website (www.perfectequation.net)
warns that the Hangover Prevention Formula will not prevent
and cautions people to drink responsibly.
Weise also advises consumers that Tex-OE was the patented
extract administered in the study, and it is different
prickly pear extract. Therefore, people who desire
the same success rate
as the study should not expect it from a substitute.